Leptin Resistance, One of the Causes of Fat Piling Up to Become Obesity Many people are mistaken, alleging that people who are obese must be caused by overeating and not being able to control themselves. In fact, cases of obesity are not that simple. Actually there are other things related to obesity, namely the hormone leptin. Resistance to this hormone turns out to be a major cause of fat accumulation in humans. How could that be? Come on, learn more about leptin resistance in the following review.
what does leptin do?
Leptin is a hormone made by fat cells. His job is to control appetite and hunger. Leptin signals the brain to let you know when the stomach feels full.
In a part of the brain called the hypothalamus, there are receptors or special substances that receive signals from the hormone leptin, which will be active if the level of leptin in the body is too high.
The hormone leptin will increase if you are full and will then give signals to the receptors. Special receptors in the hypothalamus will receive a message that your stomach is full and reduces hunger and appetite.
If the hormone leptin is too low in the body, it can cause a person to overeat.
Leptin resistance is a disorder that can cause obesity People who are obese have a lot of body fat in their fat cells. Because the hormone leptin is produced by fat cells, the amount of leptin present in a person's body is proportional to the amount of fat in the body. Therefore, fat people also have very high levels of leptin.
This level of leptin should keep people from eating, because your brain should know that you already have a lot of calories stored in the body.
However, the problem is that the leptin signal is not functioning. There is a lot of leptin but your brain can't detect it. This condition is called leptin resistance. Leptin becomes resistant and does not function properly anymore because too much fat is entering. As a result, too high levels of leptin in the body.
Currently, leptin resistance is believed to be a major biological disorder in people with obesity.
When the brain does not receive leptin signals, your brain will think that your body is starving and need food, even though you actually have more than enough stored calories.
This makes your brain change your physiology and behavior to get back fat that your brain doesn't think is available. Your brain mistakenly thinks that you have to eat so you don't starve to death, so you tend to eat more. In addition, your brain also thinks that you need to save energy, which makes you feel more lazy and makes you burn fewer calories at rest.
So, eating too much and not exercising cause overweight, but rather a result of leptin resistance
What causes leptin resistance?
According to Dr. Guyenet, some of the cell mechanisms behind leptin resistance, among others.Source = www.stephanguyenet.com
- Inflammation in parts of the hypothalamus brain may be a cause of leptin resistance.
- Having high free fatty acids in the bloodstream can increase fat metabolism in the brain and disrupt leptin signals.
- Have high leptin levels.
Almost all of these factors are increased in people with obesity. So the two conditions are interconnected with each other. Where people get fatter and leptin levels will get higher.
How to prevent leptin resistance?
The best way to find out if you have leptin resistance is to look in the mirror. If you have a lot of body fat, especially in the stomach area, then you almost certainly have leptin resistance.
To prevent leptin resistance, you only need to take Leptitox supplements made 100% from natural plants. Many people have proven it.